Bone remodeling as good as autograft
Hofmann et al. ‘Autologous Iliac Bone Graft Compared with Biphasic Hydroxyapatite and Calcium Sulfate Cement for the Treatment of Bone Defects in Tibial Plateau Fractures: A Prospective, Randomized, Open-Label, Multicenter Study’. J Bone Joint Surg Am. 2020;102(3):179-193.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508276/pdf/jbjsam-102-179.pdf
Fracture-related infection and osteomyelitis
Lorentzen et al. ‘One-stage treatment of chronic osteomyelitis with an antibiotic-loaded biocomposite and a local or free flap’. Eur J Plast Surg. 2020 https://doi.org/10.1007/s00238-020-01754-5
Link: https://link.springer.com/article/10.1007%2Fs00238-020-01754-5
Drampalos et al. ‘Augmented debridement for implant related chronic osteomyelitis with an absorbable, gentamycin loaded calcium sulfate/hydroxyapatite biocomposite.’ J Orthop. 2020;17:173-179.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919360/pdf/main.pdf
Ferguson et al. ‘Radiographic and Histological Analysis of a Synthetic Bone Graft Substitute Eluting Gentamicin in the Treatment of Chronic Osteomyelitis.’ J Bone Joint Infect. 2019;4:76-84.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470655/pdf/jbjiv04p0076.pdf
Niazi et al. ‘Adjuvant antibiotic loaded bio composite in the management of diabetic foot osteomyelitis - A multicentre study’. Foot (Edinb). 2019;39:22-27.
Link: https://www.sciencedirect.com/science/article/abs/pii/S0958259218301640?via%3Dihub
McNally et al. ‘Single-stage treatment of chronic osteomyelitis with a new absorbable, gentamicin-loaded, calcium sulphate/hydroxyapatite biocomposite: a prospective series of 100 cases.’ Bone Joint J. 2016 Sep;98-B(9):1289-96
Link: https://online.boneandjoint.org.uk/doi/epub/10.1302/0301-620X.98B9.38057
Open fracture
Aljawadi et al. ‘One‑stage combined “fix and flap” approach for complex open Gustilo–Anderson IIIB lower limbs fractures: a prospective review of 102 cases.’
Link: https://link.springer.com/article/10.1007%2Fs00402-020-03705-y